Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared with Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients, 1993-1997

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Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared with Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients, 1993-1997

Investigators: Judith Shlay, Bob Flaws, Kathryn Chaloner, Jeffrey Cohen, David Cohn, Marjorie Dehlinger, Shauna Hillman, Mitchell Max, Carol Mesard, Jill Ramser, Patricia Reichelderfer, Jack Rouff, Catherine Salveson, James Sampson, Victoria Taylor

Publication Date: March 22, 2016

Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared with Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients, 1993-1997

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The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared with Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients was conducted between 1993 and 1997 at 11 units of the Terry Beirn Community Programs for the Clinical Research on AIDS. The study was conducted to evaluate the efficacy of a standardized acupuncture regime and amitriptyline hydrochloride for relief of pain due to HIV-related peripheral neuropathy. 250 HIV-infected patients with lower extremity peripheral neuropathy were randomly assigned to receive either amitriptyline or placebo capsules (once a day) and either acupuncture or needles placed in control points (once or twice a week). The study was a randomized, placebo-controlled, clinical trial that lasted 14 weeks.

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